Researchers can easily track and isolate bit.bio’s consistent, defined, and scalable human iPSC-derived cells for the first time, opening up new applications in neurodegenerative drug discovery.
bit.bio, the global leader in cell programming technology, announces the launch of its ioTracker Cells range, starting with GFP ioMicroglia, a progressive tool designed to accelerate complex neurodegenerative disease research and drug discovery. This innovative new range represents a strategic expansion of bit.bio’s ioCells Toolkit, introducing advanced live-cell imaging assay capabilities to further enhance the functionality of its flagship products.
bit.bio will showcase its portfolio of human iPSC-derived cells at the Society for Laboratory Automation and Screening (SLAS) conference, taking place from January 25-29, 2025, in San Diego, California. The bit.bio team will be at Booth #851, present multiple poster sessions and host a panel discussion with industry experts, highlighting real-world applications on how its cells are transforming drug discovery workflows.
“With ioTracker Cells, we are empowering researchers to unravel the complexities of the human brain,” said Jonathan Milner, CEO of bit.bio. “This new range, starting with GFP ioMicroglia, reflects our mission to deliver transformative tools for biomedical research and drug discovery. Our cells are accessible to scientists worldwide through global shipping, providing a comprehensive toolkit to accelerate discoveries that have the potential to transform the understanding and treatment of devastating neurological diseases.”
bit.bio’s ioCells are human iPSC-derived cells, manufactured using the company’s deterministic cell programming technology, opti-ox™. They are widely recognised as best-in-class for their unparalleled consistency, functionality, and scalability. The ioCells portfolio now features 46 products, including ioWild Type Cells, ioDisease Model Cells, ioCRISPR-Ready Cells, and the newly introduced ioTracker Cells.
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“With GFP ioMicroglia, we’re simplifying cell visualisation in complex model systems,” said Mark Kotter, Founder of bit.bio. “We are committed to relentlessly innovating cellular tools that enable scientists to study human biology and disease. I look forward to learning how our customers will use our ioTracker cells to enable novel scientific breakthroughs.”
GFP ioMicroglia are engineered to constitutively express green fluorescent protein (GFP) in bit.bio’s well-established ioMicroglia Male wild type cells. These cells demonstrate key functionalities including phagocytosis and pro-inflammatory cytokine secretion. Assay-ready in just 10 days, GFP ioMicroglia are ideal for co-culture with other neural cell types, live-cell imaging assays to simplify assessment of microglia motility and morphology, and fluorescent activated cell sorting (FACS) workflows.
“bit.bio’s new ioTracker Cells range represents a valuable addition to our neuroscience toolkit,” said Farah Patell-Socha, Vice President of Products at bit.bio. “These cells offer researchers a more refined approach to studying neuroinflammation, neurogenesis, and neurodegenerative processes. By enabling precise tracking and isolation in complex in vitro cultures, they facilitate a deeper understanding of intercellular interactions in disease. Combined with our CRISPR-Ready cells, disease models, and genetically-matched controls, these tools provide a comprehensive foundation for advancing neurodegenerative disease research.”
Source: PRNewswire
