Amissa, an NIH-backed, AI-powered menopause care intelligence platform, announced its official launch, introducing long-missing data infrastructure to one of healthcare’s largest and most mismanaged markets.
Perimenopause and menopause affect more than 75 million U.S. women and are linked to nearly $25 billion in excess annual healthcare spending, driven largely by symptoms that go unrecognized, untreated, or unmanaged.
Amissa introduces a standardized data layer for menopause symptoms, enabling clinicians to assess severity, monitor change over time, and make more informed treatment decisions.
At launch, 10 clinical practices across the U.S. are already offering Amissa to patients, bringing structure, measurement, and clinical intelligence to a category that has historically relied on unreliable recall and inconsistent documentation.
“Amissa is the only platform built with clinicians, for clinicians, to make menopause symptom data actionable,” said Samantha Smith, Co-Founder and CEO of Amissa. “We connect providers directly to objective patient data and turn it into insight they can actually use in care.”
Turning a Chaotic Transition into Structured Intelligence
Menopause is often managed as a series of isolated complaints rather than a long-term clinical transition. Amissa was built to support longitudinal management by aggregating symptom data into a single, reviewable clinical record that fits routine care.
The platform brings together:
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Validated clinical assessments to quantify symptom severity
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Longitudinal symptom tracking designed for clinical review
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Wearable integrations with Apple Watch, Oura, Garmin, and Whoop
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Proprietary AI infrastructure that highlights patterns, promotes guidelines-driven care, and supports operational and billing workflows
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“Menopause symptoms don’t move in a straight line,” said Dr. Ariel Haddad, OB-GYN and founder of Helia Health. “When I can see what’s improving, what’s worsening, and what’s staying the same between visits, I can adjust care with confidence and show patients that their experience is being taken seriously.”
By aligning clinical documentation with the realities of managing a complex and comorbid patient population, Amissa delivers practices up to 4x ROI while reducing administrative burden.
Early Clinical Adoption Signals Clear Demand
For clinicians, the value is immediate: more impactful visits, more accurate billing, and more confident decision-making.
“When symptom trends are visible before the visit, the conversation changes,” said Jaclyn Piasta, Nurse Practitioner and founder of Monarch Health. “You spend less time extracting information and more time actually practicing medicine.”
Menopause innovation has historically operated outside the healthcare system, raising costs and limiting access. Today, employers, payers, and health systems are pushing the market toward scalable infrastructure and measurable outcomes.
“Menopause isn’t a moment it’s a decade-long health transition,” Smith added. “Amissa exists to make menopause measurable, diagnosable, and actionable at scale. The companies that win this market will be the ones that own the underlying data infrastructure. That’s what we’re building.”
Source: Amissa
